Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 8/20 | 0.41 |
| ▸ | CA2 | P00918 | 8/20 | 0.41 |
| ▸ | CA5A | P35218 | 8/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6549727 | 0.91 | ALDH1A1 (0.50) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6550985 | 0.90 | ALDH1A1 (0.49) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6728631 | 0.89 | ALDH1A1 (0.48) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6727946 | 0.89 | ALDH1A1 (0.48) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6725995 | 0.89 | F2 (0.49) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6731653 | 0.88 | SMN1; SMN2 (0.50) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6727488 | 0.87 | F2 (0.47) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6730762 | 0.86 | F2 (0.47) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6727485 | 0.85 | F2 (0.46) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6723153 | 0.85 | F2 (0.45) | ALDH1A1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1167349-B1 | Chemical amplifying type positive resist composition | SUMITOMO CHEMICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-20040224251-A1 | Positive resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-11 | — | — | US | disclosed |
| US-6548220-B2 | Containing acid generator | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-04-15 | — | — | US | disclosed |
| EP-1167349-A1 | Chemical amplifying type positive resist composition and sulfonium salt | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-02 | — | — | EP | disclosed |