SCHEMBL6551275

SCHEMBL6551275

C=C(CC(=O)OCC)C(=O)O.[KH]

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.58
MGAM O43451 1/20 0.58
SI P14410 1/20 0.58
MGAM2 Q2M2H8 1/20 0.58
ALDH1A1 P00352 5/20 0.43
TRPA1 O75762 1/20 0.43
ALOX15 P16050 3/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP1A2 P05177 1/20 0.38
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.36
SOAT1 P35610 1/20 0.36
EGLN1 Q9GZT9 1/20 0.35
NLRP3 Q96P20 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL262251 0.98 GAA (0.61) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL11694766 0.96 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL11691949 0.96 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL11694427 0.96 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL528571 0.81 HCAR2 (0.39) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL24925214 0.80 THRB (0.52) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL60515 0.80 GAA (0.61) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL14601342 0.79 HSD17B10 (0.43) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL22615751 0.79 THRB (0.50) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL10826502 0.79 GAA (0.83) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106591994-A Preparation method of hydrophilic low molecular weight distribution acrylonitrile copolymer spinning solution 中国石油化工股份有限公司 2017-04-26 CN disclosed
CN-106589223-A Hydrophilic acrylonitrile copolymer spinning raw liquid preparation method 中国石油化工股份有限公司 2017-04-26 CN disclosed
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 EP disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed