Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746238 | 0.86 | HRH3 (0.65) | HRH4HRH3KDM4EALDH1A1HRH1 | |
| SCHEMBL4746684 | 0.86 | HRH4 (0.55) | HRH4HRH3KDM4EALDH1A1TP53 | |
| SCHEMBL27457430 | 0.83 | HRH2 (0.60) | HRH4HRH3KDM4EALDH1A1TP53 | |
| SCHEMBL2087691 | 0.81 | KDM4E (0.72) | HRH4HRH3KDM4EALDH1A1RAB9A | |
| SCHEMBL2088353 | 0.80 | KDM4E (0.75) | HRH4HRH3KDM4EALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL7772340 | 0.80 | KDM4E (0.71) | HRH4HRH3KDM4EALDH1A1RAB9A | |
| SCHEMBL10901847 | 0.80 | HRH3 (0.63) | HRH3KDM4EALDH1A1KCNH2HRH1 | |
| Hydrochloric Acid SCHEMBL4224584 | 0.79 | KDM4E (0.73) | HRH4HRH3KDM4EALDH1A1RAB9A | |
| SCHEMBL7911508 | 0.79 | TP53 (0.82) | ALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL2180731 | 0.79 | TP53 (0.82) | ALDH1A1TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755385-B1 | CHELANT COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2004-02-11 | — | — | EP | disclosed |
| US-5798089-A | Chelant moieties linked to an aryl moiety by an interrupted alkylene linker | NYCOMED SALUTAR, INC. (US) | 1998-08-25 | — | — | US | disclosed |
| EP-0755385-A1 | CHELANT COMPOUNDS | NYCOMED IMAGING AS (NO) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028392-A1 | CHELANT COMPOUNDS | NYCOMED SALUTAR INC. (US) | 1995-10-26 | — | — | WO | disclosed |