Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746753 | 0.87 | KDM4E (0.52) | HRH4KDM4EALDH1A1RAB9AHRH3 | |
| SCHEMBL4743300 | 0.86 | HRH3 (0.57) | HRH4BCHEACHEHRH3 | |
| SCHEMBL6551591 | 0.86 | HRH4 (0.61) | HRH4KDM4EALDH1A1TP53TSHR | |
| SCHEMBL4814712 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1RAB9AHRH3 | |
| SCHEMBL4745391 | 0.83 | HRH3 (0.67) | HRH4KDM4EALDH1A1HRH3 | |
| SCHEMBL4746206 | 0.82 | HRH3 (0.57) | HRH3 | |
| SCHEMBL4744711 | 0.81 | HRH3 (0.56) | HRH3 | |
| SCHEMBL4745363 | 0.81 | HRH3 (0.56) | HRH3 | |
| SCHEMBL4746760 | 0.81 | HRH3 (0.51) | HRH4BCHEACHEHRH3 | |
| SCHEMBL4743798 | 0.80 | HRH4 (0.49) | HRH4KDM4EALDH1A1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |