SCHEMBL6551643

SCHEMBL6551643

CCCC(C#N)NC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22097874 1.00
SCHEMBL3345515 0.83 TSHR (0.39)
SCHEMBL13626088 0.81 TSHR (0.37)
SCHEMBL23388989 0.81 TSHR (0.33)
SCHEMBL21881958 0.78
SCHEMBL25055661 0.78
SCHEMBL9296697 0.78
SCHEMBL27941709 0.77
SCHEMBL17177422 0.77
Hydrochloric Acid SCHEMBL10939952 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8106194-B2 Pyrrolopyrimidine and pyrrolotriazine derivatives TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-31 US disclosed
US-20110137031-A1 PYRROLOPYRIMIDINE AND PYRROLOTRIAZINE DERIVATIVES TAISHO PHARMACEUTICAL CO., LTD. (JP) 2011-06-09 US disclosed
CN-1189247-C Method for reactivating catalyst for cyclizing hydrolysis of aminoitrile into lactam and use of regenerated catalyst for making lactams RHONE POULENC FIBRES (FR) 2005-02-16 CN disclosed
CN-1176073-C Method for cyclizing hydrolysis of aminonitrile compound into lactam �޵�����ά����֬�м��幫˾ 2004-11-17 CN disclosed
US-20040116691-A1 Process for cyclizing hydrolysis of an aminonitrile compound to a lactam RHODIA POLYAMIDE INTERMEDIATAES (FR) 2004-06-17 US disclosed
CN-1503783-A Method for the hydrolytic cyclisation of an aminoitrile compound to give a lactam �޵��Ǿ������м��幫˾ 2004-06-09 CN disclosed
EP-1098875-B1 METHOD FOR CYCLIZING HYDROLYSIS OF AN AMINONITRILE COMPOUND INTO LACTAM RHODIA POLYAMIDE INTERMEDIATES (FR) 2004-02-04 EP disclosed
US-6677448-B1 TREATING CATALYST, WHICH COMPRISES SOLID OXIDE, AT TEMPERATURE OF BETWEEN 300 DEGREES C. AND 600 DEGREES C. IN OXIDIZING ATMOSPHERE RHODIA FIBER & RESIN INTERMEDIATES (FR) 2004-01-13 US disclosed
EP-1370524-A1 METHOD FOR THE HYDROLYTIC CYCLISATION OF AN AMINONITRILE COMPOUND TO GIVE A LACTAM Rhodia Polyamide Intermediates (FR) 2003-12-17 EP disclosed
EP-1098705-B1 METHOD FOR REACTIVATING A CATALYST FOR CYCLIZING HYDROLYSIS OF AN AMINONITRILE INTO A LACTAM AND USE OF THE REGENERATED CATALYST FOR MAKING LACTAMS RHODIA POLYAMIDE INTERMEDIATES (FR) 2003-09-24 EP disclosed
US-6479658-B1 Method for cyclizing hydrolysis of an aminonitrile compound into lactam RHODIA FIBER & RESIN INTERMEDIATES (FR) 2002-11-12 US disclosed
WO-2002074739-A1 METHOD FOR THE HYDROLYTIC CYCLISATION OF AN AMINONITRILE COMPOUND TO GIVE A LACTAM RHODIA POLYAMIDE INTERMEDIATES (FR) 2002-09-26 WO disclosed
CN-1318048-A Process for cyclization hydrolytizing aminopressiate into lactan RHODIC FIBER AND RESIN INTERME (FR) 2001-10-17 CN disclosed
CN-1317994-A Method for reactivating catalyst for cyclizing hydrolysis of aminoitrile into lactam and use of regenerated catalyst for making lactams RHODIA POLYAMIDE INTERMEDIATES (FR) 2001-10-17 CN disclosed
EP-1098705-A1 METHOD FOR REACTIVATING A CATALYST FOR CYCLIZING HYDROLYSIS OF AN AMINONITRILE INTO A LACTAM AND USE OF THE REGENERATED CATALYST FOR MAKING LACTAMS RHODIA POLYAMIDE INTERMEDIATES (FR) 2001-05-16 EP disclosed
EP-1098875-A1 METHOD FOR CYCLIZING HYDROLYSIS OF AN AMINONITRILE COMPOUND INTO LACTAM RHODIA POLYAMIDE INTERMEDIATES (FR) 2001-05-16 EP disclosed
WO-2000004994-A1 METHOD FOR REACTIVATING A CATALYST FOR CYCLIZING HYDROLYSIS OF AN AMINONITRILE INTO A LACTAM AND USE OF THE REGENERATED CATALYST FOR MAKING LACTAMS RHODIA FIBER AND RESIN INTERMEDIATES (FR) 2000-02-03 WO disclosed
WO-2000005203-A1 METHOD FOR CYCLIZING HYDROLYSIS OF AN AMINONITRILE COMPOUND INTO LACTAM RHODIA FIBER AND RESIN INTERMEDIATES (FR) 2000-02-03 WO disclosed