Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 3/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626088 | 0.98 | TSHR (0.37) | TSHROPRM1LMNAADH1BADH1C | |
| SCHEMBL11464834 | 0.84 | TSHR (0.40) | TSHROPRM1LMNAADH1BADH1C | |
| SCHEMBL6551643 | 0.83 | — | — | |
| SCHEMBL22097874 | 0.83 | — | — | |
| SCHEMBL12529371 | 0.80 | — | — | |
| SCHEMBL9853666 | 0.77 | MAPT (0.38) | OPRM1LMNAADH1BADH1CADH1A | |
| SCHEMBL386813 | 0.77 | OPRM1 (0.36) | TSHROPRM1LMNAADH1BADH1C | |
| SCHEMBL2321613 | 0.77 | OPRM1 (0.36) | OPRM1LMNAADH1BADH1CADH1A | |
| SCHEMBL23388986 | 0.76 | TSHR (0.42) | TSHRDNM1FDPSCTSS | |
| SCHEMBL9853678 | 0.76 | MAPT (0.41) | LMNAADH1BADH1CADH1AADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042391-A2 | HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2010-04-15 | — | — | WO | disclosed |