Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 20/20 | 0.61 |
| ▸ | MMP2 | P08253 | 4/20 | 0.61 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433929 | 0.90 | BMP1 (0.59) | BMP1MMP2MMP3PDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL6429345 | 0.87 | BMP1 (0.64) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL6429991 | 0.86 | BMP1 (0.69) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL6429288 | 0.85 | BMP1 (0.62) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL5404121 | 0.85 | BMP1 (0.61) | BMP1MMP3 | |
| SCHEMBL27567375 | 0.81 | BMP1 (0.72) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL27586659 | 0.81 | BMP1 (0.72) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL27567202 | 0.79 | BMP1 (0.73) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL27567200 | 0.79 | BMP1 (0.73) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL6428411 | 0.78 | BMP1 (0.80) | BMP1MMP2MMP3PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240152-B1 | OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS | PFIZER LTD (GB) | 2004-12-08 | — | — | EP | disclosed |
| EP-1240152-A1 | OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS | Pfizer Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001047901-A1 | OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS | PFIZER LIMITED (GB) | 2001-07-05 | — | — | WO | disclosed |