Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12640922 | 1.00 | GRIK1 (0.40) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL14598192 | 1.00 | GRIK1 (0.40) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL13783789 | 0.98 | MGAM (0.38) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL6555623 | 0.85 | GRIK1 (0.43) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL13917775 | 0.82 | GRIK1 (0.46) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL13060426 | 0.82 | GRIK1 (0.42) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL14277683 | 0.78 | GRIK1 (0.42) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL4661676 | 0.75 | MGAM (0.45) | GRIK1MGAMGAASIMGAM2 | |
| SCHEMBL6356441 | 0.73 | SLC6A2 (0.35) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL29138432 | 0.71 | SLC6A2 (0.38) | GRIK1SLC6A2SLC6A3KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7847998-B2 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL, INC. (US) | 2010-12-07 | — | — | US | disclosed |
| US-7505189-B2 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL, INC. (US) | 2009-03-17 | — | — | US | disclosed |
| US-7466469-B2 | Polarizing, photochromic devices and methods of making the same | PPG INDUSTRIES OHIO, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| US-20070098968-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-05-03 | — | — | US | disclosed |
| US-20070041073-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-02-22 | — | — | US | disclosed |
| EP-0786492-B1 | Method for disposal of a plastic molded product | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-5874482-A | IMMERSING SAID THERMOSET PLASTIC MOLDED PRODUCT IN AN ALKALINE AQUEOUS SOLUTION TO PROMOTE PERMEATION AND PENETRATION OF SAID ALKALINE AQUEOUS SOLUTION INTO SAID THERMOSET PLASTIC MOLDED PRODUCT, CAUSING SOFTENING, WEAKENING | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1999-02-23 | — | — | US | disclosed |
| EP-0786492-A2 | Plastic molded product and method for disposal of the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |