SCHEMBL6551925

SCHEMBL6551925

O=C1OCCN1CCOCCO

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
PDK2 Q15119 2/20 0.39
NQO2 P16083 1/20 0.35
SCN9A Q15858 1/20 0.35
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP11B2 P19099 1/20 0.34
PIK3CD O00329 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CNR2 P34972 2/20 0.33
NSD2 O96028 1/20 0.33
PABPC1 P11940 1/20 0.33
CASP6 P55212 1/20 0.33
PAX8 Q06710 1/20 0.33
CNR1 P21554 1/20 0.33
HTR1A P08908 1/20 0.33
PER2 O15055 1/20 0.33
CRY2 Q49AN0 1/20 0.33
GRM2 Q14416 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22125049 0.83 KDM4E (0.42) KDM4EPDK2NQO2SCN9ACYP11B2
SCHEMBL20105 0.81
SCHEMBL1031978 0.78 KDM4E (0.46) KDM4EPDK2NQO2PIK3CDKMT2A
SCHEMBL18650585 0.78 MEN1 (0.40) KDM4EPDK2MEN1KMT2A
SCHEMBL10337625 0.78 NAAA (0.47) KDM4EPDK2NQO2MAPK1PIK3CD
SCHEMBL10815089 0.77 KDM4E (0.43) KDM4EPDK2NQO2SCN9AMAPK1
SCHEMBL6286812 0.77 KMT2A (0.38) KDM4EPDK2SCN9ATSHRMAPK1
SCHEMBL2608911 0.77 PIK3CD (0.46) KDM4EPDK2NQO2SCN9ACYP11B2
SCHEMBL22524825 0.77 KDM4E (0.45) KDM4EPDK2NQO2SCN9ACYP11B2
SCHEMBL10732713 0.77 KDM4E (0.45) KDM4EPDK2NQO2SCN9ACYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885941-B1 Ink jet inks containing oxazolidinones XEROX CORP (US) 2004-02-18 EP claimed
US-5882389-A WATER, COLOR AND OXAZOLIDINONE XEROX CORPORATION (US) 1999-03-16 US claimed
EP-0885941-B1 Ink jet inks containing oxazolidinones XEROX CORP (US) 2004-02-18 EP disclosed
US-6225370-B1 FOR USE WITH INK JET PRINTERS LEXMARK INTERNATIONAL, INC. 2001-05-01 US disclosed
US-5882389-A WATER, COLOR AND OXAZOLIDINONE XEROX CORPORATION (US) 1999-03-16 US disclosed
EP-0885941-A1 Ink jet inks containing oxazolidinones Xerox Corporation (US) 1998-12-23 EP disclosed