Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.81 |
| ▸ | PPARA | Q07869 | 4/20 | 0.81 |
| ▸ | PPARD | Q03181 | 2/20 | 0.81 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6356266 | 0.91 | PPARG (0.68) | PPARGPPARAPPARDSOAT1 | |
| Gsk-9578 SCHEMBL30475595 | 0.90 | PPARG (1.00) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL20280514 | 0.90 | PPARG (1.00) | PPARGPPARAPPARDSOAT1 | |
| Gsk-9578 SCHEMBL68327 | 0.90 | PPARG (1.00) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL16521916 | 0.90 | PPARG (0.87) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL17471275 | 0.89 | PPARG (0.85) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL2415650 | 0.83 | PPARG (0.57) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL28023966 | 0.81 | PPARG (0.72) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL6356255 | 0.81 | PPARG (0.82) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL6545314 | 0.81 | PPARG (0.82) | PPARGPPARAPPARDSOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149063-B1 | UREIDO-THIOBUTYRIC ACID DERIVATIVES AS PPAR-AGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1149063-A2 | UREIDO-THIOBUTYRIC ACID DERIVATIVES AS PPAR-AGONISTS | GLAXO GROUP LIMITED (GB) | 2001-10-31 | — | — | EP | disclosed |
| US-6306854-B1 | ARYLTHIOALKYLACIDS AND ALKYL UREAS | GLAXOSMITHKLINE | 2001-10-23 | — | — | US | disclosed |
| WO-2000023407-A2 | UREIDO-THIOBUTYRIC ACID DERIVATIVES AS PPAR-AGONISTS | GLAXO GROUP LIMITED (GB) | 2000-04-27 | — | — | WO | disclosed |