Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.72 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.56 |
| ▸ | FDPS | P14324 | 4/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5690430 | 0.84 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL15876022 | 0.84 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL9307335 | 0.84 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL1059770 | 0.84 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL1060233 | 0.84 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL5691911 | 0.84 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL5691588 | 0.84 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL745344 | 0.84 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| Bromide SCHEMBL6049732 | 0.82 | LAP3 (0.96) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| Bromide SCHEMBL6049728 | 0.82 | LAP3 (0.96) | LAP3S1PR2S1PR1S1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485391-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003080630-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2003-10-02 | — | — | WO | disclosed |