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SCHEMBL6552216

SCHEMBL6552216

N=C(N)NCCCC(NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)CCCCCCCCCCCCCCCCC(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCNC(=N)N)C(=O)CCl)C(=O)CCl

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 10/20 0.61
▸ NPY5R Q15761 6/20 0.61
▸ NPY1R P25929 5/20 0.61
▸ NPY2R P49146 3/20 0.61
▸ CTSG P08311 1/20 0.58
▸ CMA1 P23946 1/20 0.58
▸ KISS1R Q969F8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6046826 1.00 NPY4R (0.61) NPY4RNPY5RNPY1RNPY2RCTSG
SCHEMBL6046817 1.00 NPY4R (0.61) NPY4RNPY5RNPY1RNPY2RCTSG
SCHEMBL6046840 0.93 NPY4R (0.54) NPY4RNPY5RNPY1RNPY2RCTSG
SCHEMBL6046841 0.91 NPY4R (0.51) NPY4RNPY5RNPY1RNPY2RCTSG
SCHEMBL6046837 0.90 NPY4R (0.48) NPY4RNPY5RNPY1RNPY2RCTSG
SCHEMBL6805280 0.88 NPY4R (0.54) NPY4RNPY5RNPY1RNPY2RCTSG
SCHEMBL7440667 0.85 NPY4R (0.58) NPY4RNPY5RNPY1RNPY2R
SCHEMBL6046846 0.84 NPY4R (0.45) NPY4RNPY5RNPY1RNPY2RCTSG
SCHEMBL6664909 0.84 FOLH1 (0.53) NPY4RNPY5RNPY1RNPY2RCTSG
SCHEMBL6554289 0.83 NPY4R (0.43) NPY4RNPY5RNPY1RNPY2RCTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1485476-A2 DIMERIC TF ANTAGONIST NOVO NORDISK A/S (DK) 2004-12-15 — — EP disclosed
WO-2003076461-A2 DIMERIC TF ANTAGONIST COMPRISING TWO FACTOR VII POLYPEPTIDES NOVO NORDISK A/S (DK) 2003-09-18 — — WO disclosed