SCHEMBL6554289

N=C(N)NCCCC(NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)N(C(=O)C(N)=O)C(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCNC(=N)N)C(=O)CCl)C(=O)CCl

nearest known ligand 0.43

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	15/20	0.43

▸	NPY1R	P25929	9/20	0.43

▸	NPY5R	Q15761	8/20	0.43

▸	NPY2R	P49146	5/20	0.43

▸	GNPAT	O15228	1/20	0.40

▸	CTSG	P08311	1/20	0.40

▸	CMA1	P23946	1/20	0.40

▸	QRFPR	Q96P65	1/20	0.40

▸	CTSL	P07711	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6046837	0.86	NPY4R (0.48)	NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL6805280	0.84	NPY4R (0.54)	NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL6046817	0.83	NPY4R (0.61)	NPY4RNPY1RNPY5RNPY2RCTSG
SCHEMBL6552216	0.83	NPY4R (0.61)	NPY4RNPY1RNPY5RNPY2RCTSG
SCHEMBL6046826	0.83	NPY4R (0.61)	NPY4RNPY1RNPY5RNPY2RCTSG
SCHEMBL6046841	0.80	NPY4R (0.51)	NPY4RNPY1RNPY5RNPY2RCTSG
SCHEMBL6046846	0.79	NPY4R (0.45)	NPY4RNPY1RNPY5RNPY2RCTSG
SCHEMBL6802259	0.78	LMNA (0.55)	NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL6664909	0.78	FOLH1 (0.53)	NPY4RNPY1RNPY5RNPY2RCTSG
SCHEMBL6046840	0.77	NPY4R (0.54)	NPY4RNPY1RNPY5RNPY2RCTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1485476-A2	DIMERIC TF ANTAGONIST	NOVO NORDISK A/S (DK)	2004-12-15	—	—	EP	disclosed
WO-2003076461-A2	DIMERIC TF ANTAGONIST COMPRISING TWO FACTOR VII POLYPEPTIDES	NOVO NORDISK A/S (DK)	2003-09-18	—	—	WO	disclosed