Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978476 | 0.82 | GABRA1 (0.36) | GABRA1GABRB2TYR | |
| SCHEMBL2170750 | 0.68 | ATM (0.43) | — | |
| SCHEMBL2170748 | 0.68 | ATM (0.43) | — | |
| SCHEMBL17363836 | 0.68 | ATM (0.43) | — | |
| SCHEMBL16953048 | 0.66 | GABRA1 (0.34) | GABRA1GABRB2 | |
| SCHEMBL21556465 | 0.66 | MAPT (0.44) | TYR | |
| SCHEMBL6916487 | 0.64 | FABP3 (0.41) | GABRA1GABRB2 | |
| Hydrogen Peroxide SCHEMBL3271571 | 0.64 | FABP3 (0.52) | GABRA1GABRB2TYR | |
| Hydrogen Peroxide SCHEMBL3267226 | 0.64 | FABP3 (0.52) | GABRA1GABRB2TYR | |
| Hydrogen Peroxide SCHEMBL11574983 | 0.64 | FABP3 (0.52) | GABRA1GABRB2TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1388534-A2 | 2,4-pentadienoic acid derivatives having selective activity for retinoid X (RXR) receptors | Allergan, Inc. (US) | 2004-02-11 | — | — | EP | disclosed |
| EP-1117628-B1 | 2, 4-PENTADIENOIC ACID DERIVATIVES HAVING SELECTIVE ACTIVITY FOR RETINOID X (RXR) RECEPTORS | ALLERGAN INC (US) | 2003-11-19 | — | — | EP | disclosed |
| US-6403638-B1 | COMPOUND FOR USE IN TREATING SKIN DISEASES AND DISORDERS, AND FOR TREATING HYPERVITAMINOSIS A SYNDROME | ALLERGAN SALES, INC. | 2002-06-11 | — | — | US | disclosed |
| WO-2001070662-A2 | 2,4-PENTADIENOIC ACID DERIVATIVES HAVING SELECTIVE ACTIVITY FOR RETINOID X (RXR) RECEPTORS | ALLERGAN , INC. (US) | 2001-09-27 | — | — | WO | disclosed |
| EP-1117628-A1 | 2, 4-PENTADIENOIC ACID DERIVATIVES HAVING SELECTIVE ACTIVITY FOR RETINOID X (RXR) RECEPTORS | Allergan Sales, Inc. (US) | 2001-07-25 | — | — | EP | disclosed |
| US-6147224-A | 2,4-pentadienoic acid derivatives having selective activity for retinoid X (RXR) receptors | ALLERGAN SALES, INC. (US) | 2000-11-14 | — | — | US | disclosed |
| WO-2000020370-A1 | 2, 4-PENTADIENOIC ACID DERIVATIVES HAVING SELECTIVE ACTIVITY FOR RETINOID X (RXR) RECEPTORS | ALLERGAN SALES, INC. (US) | 2000-04-13 | — | — | WO | disclosed |