Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8606765 | 1.00 | TSHR (0.48) | TSHRALDH1A1TAAR1AKT1AKT2 | |
| Tert-Butylbenzene SCHEMBL27715546 | 0.85 | TSHR (0.46) | TSHRALDH1A1TAAR1NPC1JAK2 | |
| Trifluoromethylbenzene SCHEMBL27930053 | 0.83 | TSHR (0.54) | TSHRALDH1A1LTA4HADORA3TDP1 | |
| Ethyl Chloride SCHEMBL29011213 | 0.82 | TAAR1 (0.50) | TSHRALDH1A1TAAR1AKT1AKT2 | |
| Trifluoromethylbenzene SCHEMBL28122230 | 0.81 | TSHR (0.52) | TSHRALDH1A1LTA4HDNM1HTR2A | |
| Stearic Acid SCHEMBL29050833 | 0.80 | GPR84 (0.55) | TSHRALDH1A1ESR1TDP1 | |
| Propane SCHEMBL29199490 | 0.80 | TAAR1 (0.52) | TSHRALDH1A1TAAR1AKT1AKT2 | |
| Aniline SCHEMBL27532785 | 0.79 | TSHR (0.54) | TSHRALDH1A1NPC1JAK2RAB9A | |
| Stearic Acid SCHEMBL29050850 | 0.78 | GPR84 (0.53) | TSHRALDH1A1ESR1TDP1 | |
| Biphenyl SCHEMBL28541047 | 0.78 | TSHR (0.59) | TSHRALDH1A1NPC1JAK2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0884044-B1 | HAIR TREATMENT COMPOSITION | KAO CORP (JP) | 2004-12-22 | — | — | EP | disclosed |
| US-6099828-A | COMPOSITION THAT CAN MAINTAIN ITS CONDITIONING EFFECT OVER A LONG PERIOD OF TIME; ALSO CONTAINING ACID DYE | KAO CORPORATION (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0884044-A1 | HAIRTREATMENT COMPOSITION | Kao Corporation (JP) | 1998-12-16 | — | — | EP | disclosed |