Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972984 | 0.81 | CA9 (0.50) | KMT2APKMHTR6CA12CA9 | |
| SCHEMBL10336123 | 0.79 | APOBEC3G (0.47) | APOBEC3GKMT2APKMHTR6ESR1 | |
| SCHEMBL5810584 | 0.79 | APOBEC3G (0.47) | APOBEC3GKMT2APKMHTR6ESR1 | |
| SCHEMBL6393197 | 0.78 | ALDH1A1 (0.49) | APOBEC3GKMT2APKMESR1CA12 | |
| SCHEMBL5883809 | 0.76 | APOBEC3G (0.44) | APOBEC3GKMT2APKMHTR6ESR1 | |
| SCHEMBL10824170 | 0.75 | APOBEC3G (0.47) | APOBEC3GKMT2APKMHSD11B1 | |
| SCHEMBL2972423 | 0.74 | APOBEC3G (0.41) | APOBEC3GKMT2AESR1CA12CA9 | |
| SCHEMBL9709553 | 0.72 | ALDH1A1 (0.46) | KMT2APKMHTR6CA12CA9 | |
| SCHEMBL11347290 | 0.72 | APOBEC3G (0.58) | APOBEC3GKMT2APKMHTR6ESR1 | |
| SCHEMBL296001 | 0.70 | KMT2A (0.48) | KMT2APKMHTR6CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107823184-A | The preparation method of isotope of redox-sensitive induction pH response nano pharmaceutical carriers and application | 中国医学科学院生物医学工程研究所 | 2018-03-23 | — | — | CN | disclosed |
| CN-101212973-B | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives as medicaments for the treatment of infertility | ORGANON NV | 2011-11-16 | — | — | CN | disclosed |
| CN-101212973-A | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives as medicaments for the treatment of infertility | ORGANON NV (NL) | 2008-07-02 | — | — | CN | disclosed |
| EP-1489069-A2 | Preparation of sulfonyl imine compounds | E.I. du Pont de Nemours and Company (US) | 2004-12-22 | — | — | EP | disclosed |
| EP-1216227-B1 | PREPARATION OF SULFONYL IMINE COMPOUNDS | DU PONT (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2001023352-A9 | PREPARATION OF SULFONYL IMINE COMPOUNDS | DU PONT (US) | 2002-12-27 | — | — | WO | disclosed |
| EP-1216227-A2 | PREPARATION OF SULFONYL IMINE COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-06-26 | — | — | EP | disclosed |
| US-6380429-B1 | OXIDATION OF SULFONAMIDE | E. I. DU PONT NEMOURS AND COMPANY | 2002-04-30 | — | — | US | disclosed |
| WO-2001023352-A2 | PREPARATION OF SULFONYL IMINE COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-04-05 | — | — | WO | disclosed |
| CN-1047220-A | PAN GRANULATION | DU PONT (US) | 1990-11-28 | — | — | CN | disclosed |