SCHEMBL6552702

SCHEMBL6552702

C/C=C/COC(=O)CCCCC(=O)OC/C=C/C

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
DGKA P23743 2/20 0.45
ALDH1A1 P00352 3/20 0.42
CYP3A4 P08684 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
ALOX15 P16050 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PAM P19021 2/20 0.41
NR1I2 O75469 1/20 0.40
PGR P06401 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
PTGS2 P35354 1/20 0.40
PDE4D Q08499 1/20 0.40
CYP1A2 P05177 1/20 0.40
MAPT P10636 1/20 0.38
LMNA P02545 2/20 0.37
DNM1 Q05193 1/20 0.37
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6550916 1.00 TSHR (0.52) TSHRDGKAALDH1A1CYP3A4TDP1
SCHEMBL6551855 0.98 TSHR (0.55) TSHRDGKAALDH1A1CYP3A4TDP1
SCHEMBL6552434 0.98 TSHR (0.55) TSHRDGKAALDH1A1CYP3A4TDP1
SCHEMBL448049 0.90 ADRA2A (0.41) TSHRDGKAALDH1A1CYP3A4TDP1
SCHEMBL38650669 0.90 TSHR (0.49) TSHRALDH1A1TDP1ALOX15HSD17B10
SCHEMBL29283199 0.90 TSHR (0.49) TSHRDGKAALDH1A1CYP3A4TDP1
SCHEMBL2438353 0.90 TSHR (0.68) TSHRDGKAALDH1A1PAMMAPT
SCHEMBL2437349 0.90 TSHR (0.68) TSHRDGKAALDH1A1PAMMAPT
SCHEMBL9122870 0.89 TSHR (0.56) TSHRDGKAALDH1A1CYP3A4TDP1
SCHEMBL9122873 0.89 TSHR (0.56) TSHRDGKAALDH1A1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3718743-B1 A METHOD FOR MANUFACTURING COMPOSITE MATERIAL HAVING SELF-SUPPORTING CAPABILITY IN A MELT STATE THAT IS SUITABLE FOR FUSED GRANULATE FABRICATION AND A PRODUCT THEREOF UPM KYMMENE CORP (FI) 2021-06-02 EP disclosed
EP-3718743-A1 A METHOD FOR MANUFACTURING COMPOSITE MATERIAL HAVING SELF-SUPPORTING CAPABILITY IN A MELT STATE THAT IS SUITABLE FOR FUSED GRANULATE FABRICATION AND A PRODUCT THEREOF UPM-Kymmene Corporation (FI) 2020-10-07 EP disclosed
EP-0786492-B1 Method for disposal of a plastic molded product MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2004-12-15 EP disclosed
US-5874482-A IMMERSING SAID THERMOSET PLASTIC MOLDED PRODUCT IN AN ALKALINE AQUEOUS SOLUTION TO PROMOTE PERMEATION AND PENETRATION OF SAID ALKALINE AQUEOUS SOLUTION INTO SAID THERMOSET PLASTIC MOLDED PRODUCT, CAUSING SOFTENING, WEAKENING MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1999-02-23 US disclosed
EP-0786492-A2 Plastic molded product and method for disposal of the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1997-07-30 EP disclosed