⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15632758 | 0.77 | — | — | |
| SCHEMBL16418408 | 0.76 | TSHR (0.35) | — | |
| SCHEMBL6579598 | 0.74 | — | — | |
| SCHEMBL1100317 | 0.73 | — | — | |
| SCHEMBL7071793 | 0.72 | — | — | |
| Bicarbonate SCHEMBL31496456 | 0.69 | — | — | |
| SCHEMBL2505557 | 0.67 | — | — | |
| SCHEMBL15234347 | 0.67 | PAM (0.43) | — | |
| SCHEMBL5574246 | 0.67 | — | — | |
| SCHEMBL28353573 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3267794-B1 | BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | UNIV YALE (US) | 2020-09-09 | — | — | EP | claimed |
| EP-3114128-B1 | NOVEL 6-FUSED HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2019-01-02 | — | — | EP | claimed |
| EP-1023431-B1 | HARD SURFACE CLEANING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | PROCTER & GAMBLE (US) | 2004-12-15 | — | — | EP | claimed |
| EP-0955295-B1 | Therapeutically active levorotatory and dextrorotatory 1-((4-chlorophenyl)phenylmethyl) piperazines | UCB SA (BE) | 2004-05-19 | — | — | EP | claimed |
| EP-1413307-A1 | Therapeutically active levorotatory and dextrorotatory 1-(4-chlorophenyl)phenylmethyl piperazines | UCB S.A. (BE) | 2004-04-28 | — | — | EP | claimed |
| EP-0888440-B1 | GLASS CLEANING COMPOSITIONS CONTAINING BLOOMING PERFUME | PROCTER & GAMBLE (US) | 2003-01-29 | — | — | EP | claimed |
| EP-0888433-B1 | GLASS CLEANER COMPOSITIONS HAVING GOOD FILMING/STREAKING CHARACTERISTICS CONTAINING AMINE OXIDE POLYMERS FUNCTIONALITY | PROCTER & GAMBLE (US) | 2002-11-13 | — | — | EP | claimed |
| EP-0804536-B1 | GLASS CLEANER COMPOSITIONS | PROCTER & GAMBLE (US) | 2000-01-12 | — | — | EP | claimed |
| EP-0955295-A1 | Therapeutically active levorotatory and dextrorotatory 1-((4-chlorophenyl)phenylmethyl) piperazines | UCB, S.A. (BE) | 1999-11-10 | — | — | EP | claimed |
| EP-0617028-A1 | Enantiomers of 1-(4-chlorophenyl)phenylmethyl)-4-(4-methylphenyl)sulfonyl piperazine | U C B, S.A. (BE) | 1994-09-28 | — | — | EP | claimed |
| EP-0378604-B1 | 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES | ERBA CARLO SPA (IT) | 1994-03-02 | — | — | EP | claimed |
| EP-0955295-B1 | Therapeutically active levorotatory and dextrorotatory 1-((4-chlorophenyl)phenylmethyl) piperazines | UCB SA (BE) | 2004-05-19 | — | — | EP | disclosed |
| EP-1413307-A1 | Therapeutically active levorotatory and dextrorotatory 1-(4-chlorophenyl)phenylmethyl piperazines | UCB S.A. (BE) | 2004-04-28 | — | — | EP | disclosed |
| EP-1413307-A1 | Therapeutically active levorotatory and dextrorotatory 1-(4-chlorophenyl)phenylmethyl piperazines | UCB S.A. (BE) | 2004-04-28 | — | — | EP | disclosed |
| EP-0617028-B1 | Enantiomers of 1-[(4-chlorophenyl)phenylmethyl]-4-[(4-methylphenyl)sulfonyl] piperazine | UCB SA (BE) | 2000-06-14 | — | — | EP | disclosed |
| EP-0955295-A1 | Therapeutically active levorotatory and dextrorotatory 1-((4-chlorophenyl)phenylmethyl) piperazines | UCB, S.A. (BE) | 1999-11-10 | — | — | EP | disclosed |
| EP-0617028-A1 | Enantiomers of 1-(4-chlorophenyl)phenylmethyl)-4-(4-methylphenyl)sulfonyl piperazine | U C B, S.A. (BE) | 1994-09-28 | — | — | EP | disclosed |
| WO-1991018888-A1 | N-SUBSTITUTED-1,2,4-TRIAZOLONE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-12 | — | — | WO | disclosed |