⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6551602 | 0.88 | DRD2 (0.34) | — | |
| SCHEMBL6551561 | 0.88 | DRD2 (0.30) | — | |
| SCHEMBL6552901 | 0.81 | DRD2 (0.36) | — | |
| SCHEMBL6553050 | 0.81 | DRD2 (0.42) | — | |
| SCHEMBL6552858 | 0.76 | DAO (0.32) | — | |
| SCHEMBL6552783 | 0.71 | TAAR1 (0.33) | — | |
| SCHEMBL6551590 | 0.67 | TAAR1 (0.59) | — | |
| SCHEMBL6812077 | 0.67 | HTR1D (0.43) | — | |
| SCHEMBL5097946 | 0.67 | HTR1D (0.43) | — | |
| SCHEMBL6552136 | 0.66 | HPGD (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409476-B1 | PHARMACEUTICAL COMPOUNDS WITH SEROTONIN RECEPTOR ACTIVITY | LILLY CO ELI (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20040180883-A1 | Pharmaceutical compounds with serotonin receptor activity | GILMORE JEREMY (GB) | 2004-09-16 | — | — | US | disclosed |
| EP-1409476-A1 | PHARMACEUTICAL COMPOUNDS WITH SEROTONIN RECEPTOR ACTIVITY | ELI LILLY AND COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003006455-A1 | PHARMACEUTICAL COMPOUNDS WITH SEROTONIN RECEPTOR ACTIVITY | ELI LILLY AND COMPANY (US) | 2003-01-23 | — | — | WO | disclosed |