Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5830141 | 1.00 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3HTR1AHTR6 | |
| SCHEMBL6553682 | 0.96 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3HTR1AHTR6 | |
| SCHEMBL5830039 | 0.96 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3HTR1AHTR6 | |
| SCHEMBL1021480 | 0.85 | SLC6A3 (0.68) | SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL1021477 | 0.85 | SLC6A3 (0.68) | SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL1335541 | 0.84 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3HTR6 | |
| SCHEMBL6552082 | 0.84 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3HTR1AHTR6 | |
| SCHEMBL5829797 | 0.84 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3HTR1AHTR6 | |
| SCHEMBL5829700 | 0.84 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3HTR1AHTR6 | |
| SCHEMBL5829453 | 0.84 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3HTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133494-B1 | 8-AZABICYCLO 3.2.1]OCT-2-ENE AND -OCTANE DERIVATIVES | NEUROSEARCH AS (DK) | 2004-02-18 | — | — | EP | claimed |