Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26107092 | 0.86 | ALDH1A1 (0.33) | HIF1ATSHRALDH1A1 | |
| SCHEMBL3911215 | 0.79 | HIF1A (0.41) | HIF1ATSHRFAAHTRPV1ALDH1A1 | |
| SCHEMBL3918058 | 0.76 | TSHR (0.42) | HIF1ATSHRFAAHTRPV1ALDH1A1 | |
| SCHEMBL31165824 | 0.76 | TSHR (0.30) | TSHR | |
| SCHEMBL25532072 | 0.75 | — | — | |
| SCHEMBL18784631 | 0.73 | — | — | |
| SCHEMBL3911217 | 0.73 | TSHR (0.41) | HIF1ATSHRFAAHTRPV1ALDH1A1 | |
| SCHEMBL9815990 | 0.72 | — | — | |
| SCHEMBL11209296 | 0.71 | ALDH1A1 (0.33) | HIF1ATSHRALDH1A1 | |
| SCHEMBL2638555 | 0.71 | ALDH1A1 (0.33) | HIF1ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000950-B1 | Novel indanylidene compounds | HOFFMANN LA ROCHE (CH) | 2004-02-25 | — | — | EP | disclosed |