Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 8/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501546 | 0.80 | NOS2 (0.61) | NOS2SLC6A4CYP2D6SLC6A2 | |
| Oxalic Acid SCHEMBL6493096 | 0.75 | NOS2 (0.67) | NOS2SLC6A4CYP2D6SLC6A2 | |
| SCHEMBL6050442 | 0.73 | NOS2 (0.69) | NOS2SLC6A4CYP2D6SLC6A2 | |
| SCHEMBL6050219 | 0.73 | NOS2 (0.69) | NOS2SLC6A4CYP2D6SLC6A2 | |
| SCHEMBL6490842 | 0.73 | NOS2 (0.47) | NOS2SLC6A4CYP2D6SLC6A2 | |
| Oxalic Acid SCHEMBL6497943 | 0.68 | NOS2 (0.47) | NOS2SLC6A4CYP2D6SLC6A2 | |
| SCHEMBL25412202 | 0.60 | NOS2 (0.68) | NOS2SLC6A4CYP2D6SLC6A2 | |
| SCHEMBL6491496 | 0.60 | NOS2 (0.65) | NOS2SLC6A4CYP2D6SLC6A2MET | |
| SCHEMBL6491319 | 0.59 | NOS2 (0.64) | NOS2SLC6A4CYP2D6SLC6A2 | |
| SCHEMBL6495507 | 0.59 | CYP2D6 (0.41) | NOS2SLC6A4CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263711-B1 | NOVEL USE OF PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-12-15 | — | — | EP | claimed |