SCHEMBL6553883

SCHEMBL6553883

[CH2]CCCC(=O)Oc1cccc(OC)c1OC

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 2/20 0.46
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
KDM4E B2RXH2 2/20 0.42
RECQL P46063 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAPT P10636 3/20 0.42
HPGD P15428 2/20 0.42
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
POLM Q9NP87 1/20 0.39
POLK Q9UBT6 1/20 0.39
POLL Q9UGP5 1/20 0.39
POLH Q9Y253 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4646799 0.86 KMT2A (0.51) KMT2AMEN1KDM4ERECQLSMN1; SMN2
SCHEMBL4643841 0.82 SRC (0.50) NFE2L2KMT2AMEN1KDM4ESMN1; SMN2
SCHEMBL15558412 0.80 MEN1 (0.57) NFE2L2KMT2AMEN1KDM4ERECQL
SCHEMBL14471561 0.79 NFE2L2 (0.51) NFE2L2KMT2AKDM4ESMN1; SMN2HPGD
SCHEMBL15547554 0.79 POLM (0.54) KMT2AMEN1KDM4ERECQLSMN1; SMN2
SCHEMBL15558619 0.78 POLM (0.56) KMT2AMEN1KDM4ERECQLSMN1; SMN2
SCHEMBL15548599 0.78 POLM (0.56) KMT2AMEN1KDM4ERECQLSMN1; SMN2
SCHEMBL15546871 0.78 HPGD (0.43) NFE2L2KMT2AMEN1KDM4ERECQL
SCHEMBL20598644 0.77 MAPT (0.47) NFE2L2KMT2AMEN1KDM4EMAPT
SCHEMBL3824327 0.77 SMN1; SMN2 (0.56) KMT2AMEN1KDM4ERECQLSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed