Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554212 | 0.84 | ADRB3 (0.36) | ADRB3ADRB1MEN1POLBKMT2A | |
| SCHEMBL6540456 | 0.83 | PSEN1 (0.39) | ADRB3ADRB1MEN1POLBKMT2A | |
| SCHEMBL6540463 | 0.83 | PSEN1 (0.39) | ADRB3ADRB1MEN1POLBKMT2A | |
| SCHEMBL6540461 | 0.83 | PSEN1 (0.39) | ADRB3ADRB1MEN1POLBKMT2A | |
| SCHEMBL6802974 | 0.83 | ADRB3 (0.43) | ADRB3ADRB1MEN1POLBKMT2A | |
| SCHEMBL6805795 | 0.82 | ADRB3 (0.44) | ADRB3ADRB1MEN1POLBKMT2A | |
| SCHEMBL6805800 | 0.82 | ADRB3 (0.44) | ADRB3ADRB1MEN1POLBKMT2A | |
| SCHEMBL6799695 | 0.82 | ADRB3 (0.36) | ADRB3ADRB1MEN1POLBKMT2A | |
| SCHEMBL6678311 | 0.82 | ADRB3 (0.51) | ADRB3ADRB1MEN1POLBKMT2A | |
| SCHEMBL6540568 | 0.82 | OPRK1 (0.43) | ADRB3ADRB1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |