Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.55 |
| ▸ | PGR | P06401 | 8/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.55 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622641 | 0.88 | NR3C1 (0.49) | NR3C1PGRNR3C2AR | |
| SCHEMBL6556479 | 0.85 | NR3C1 (0.71) | NR3C1PGRNR3C2AR | |
| SCHEMBL5645301 | 0.85 | NR3C1 (0.49) | NR3C1PGRNR3C2AR | |
| SCHEMBL5643383 | 0.84 | NR3C1 (0.53) | NR3C1PGRNR3C2AR | |
| SCHEMBL4002508 | 0.80 | NR3C1 (0.65) | NR3C1PGRNR3C2AR | |
| SCHEMBL5641716 | 0.79 | NR3C1 (0.59) | NR3C1PGRNR3C2AR | |
| SCHEMBL4278672 | 0.79 | NR3C1 (0.52) | NR3C1PGRNR3C2AR | |
| SCHEMBL5644782 | 0.79 | NR3C1 (0.47) | NR3C1PGRNR3C2AR | |
| SCHEMBL5645477 | 0.78 | NR3C1 (0.51) | NR3C1PGRNR3C2AR | |
| SCHEMBL5645065 | 0.78 | NR3C1 (0.53) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133486-B1 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AG (DE) | 2004-12-22 | — | — | EP | disclosed |
| US-6323199-B1 | AROMATIC HETEROCYCLIC HYDROXY AMINES OR AMIDES FOR TREATMENT OF INFLAMMATION | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-11-27 | — | — | US | disclosed |