SCHEMBL6554305

SCHEMBL6554305

C=[Hf](C1C=Cc2ccccc21)C1C=Cc2ccccc21.CN(C(N(C)c1ccccc1)=[Hf](C1C=Cc2ccccc21)C1C=Cc2ccccc21)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.30
PHGDH O43175 1/20 0.30
MGLL Q99685 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8380999 0.78 HTR2A (0.38)
Fluoride SCHEMBL6059223 0.76 HTR2A (0.36)
Hydrochloric Acid SCHEMBL817704 0.76 HTR2A (0.36)
Hydrochloric Acid SCHEMBL7645798 0.76 HTR2A (0.36)
Hydrochloric Acid SCHEMBL4469522 0.76 HTR2A (0.36)
SCHEMBL6552988 0.72 TSHR (0.44)
Hydrochloric Acid SCHEMBL818469 0.69 HTR2A (0.33)
Hydrochloric Acid SCHEMBL7642478 0.69 HTR2A (0.33)
Hydrochloric Acid SCHEMBL7941400 0.67 SIGMAR1 (0.34)
Hydrochloric Acid SCHEMBL7944167 0.66 ATM (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0834515-B1 New Organotransition Metal Compounds KANTO KAGAKU (JP) 2004-02-25 EP disclosed
US-5859276-A Organotransition metal compounds KANTO KAGAKU KABUSHIKI KAISHA (JP) 1999-01-12 US disclosed
EP-0834515-A2 Transition-metal containing organic compounds and their use as catalysts for olefin polymerization KANTO KAGAKU KABUSHIKI KAISHA (JP) 1998-04-08 EP disclosed