Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554385 | 0.88 | LMNA (0.36) | MAPTALDH1A1SIGMAR1KDM4EHTR2A | |
| SCHEMBL3798506 | 0.83 | HTR2A (0.38) | SIGMAR1KDM4EHTR2ALMNATP53 | |
| SCHEMBL6552975 | 0.83 | TSHR (0.44) | SIGMAR1KDM4EHTR2ALMNATP53 | |
| Hydrochloric Acid SCHEMBL7644899 | 0.82 | HTR2A (0.36) | SIGMAR1KDM4EHTR2ALMNATP53 | |
| Hydrochloric Acid SCHEMBL4475457 | 0.82 | HTR2A (0.36) | SIGMAR1KDM4EHTR2ALMNATP53 | |
| Biphenyl SCHEMBL9342597 | 0.80 | HTR2A (0.33) | ALDH1A1SIGMAR1KDM4EHTR2ALMNA | |
| SCHEMBL7934755 | 0.75 | KDM4E (0.34) | SIGMAR1KDM4EHTR2ALMNATP53 | |
| SCHEMBL8162951 | 0.74 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL7937107 | 0.72 | CYP2D6 (0.31) | CYP2D6 | |
| SCHEMBL5183638 | 0.70 | HTR2A (0.39) | SIGMAR1KDM4EHTR2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834515-B1 | New Organotransition Metal Compounds | KANTO KAGAKU (JP) | 2004-02-25 | — | — | EP | disclosed |
| EP-0834514-B1 | Process for synthesizing metallocene compounds | KANTO KAGAKU (JP) | 2003-10-22 | — | — | EP | disclosed |
| US-5892075-A | Process for synthesizing metallocene compounds | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0834514-A2 | Process for synthesizing metallocene compounds | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1998-04-08 | — | — | EP | disclosed |
| EP-0834515-A2 | Transition-metal containing organic compounds and their use as catalysts for olefin polymerization | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1998-04-08 | — | — | EP | disclosed |