SCHEMBL6554374

SCHEMBL6554374

C=Cc1ccc(Cl)c(S(=O)(=O)O)c1C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
METAP2 P50579 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CYP2C9 P11712 1/20 0.34
GSTO1 P78417 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6554325 0.82 TDP1 (0.37) TDP1ALDH1A1CYP2C9
SCHEMBL11837076 0.76 TDP1 (0.41) TDP1ALDH1A1CYP2C9GSTO1
SCHEMBL6685387 0.75 TDP1 (0.37) TDP1METAP2ALDH1A1
SCHEMBL8356169 0.75 ALDH1A1 (0.50) TDP1ALDH1A1CYP2C9
SCHEMBL18289495 0.75 TDP1 (0.46) TDP1ALDH1A1
SCHEMBL7914834 0.73 ALDH1A1 (0.44) ALDH1A1
SCHEMBL9232347 0.73 ALDH1A1 (0.44) TDP1ALDH1A1CYP2C9
SCHEMBL9431949 0.73 ALDH1A1 (0.38) ALDH1A1
SCHEMBL11832328 0.72 ALDH1A1 (0.35) TDP1METAP2ALDH1A1
SCHEMBL18506337 0.71 ALDH1A1 (0.43) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0841415-B1 Fine inorganic particles containing fibres and method for forming the same JAPAN EXLAN CO LTD (JP) 2004-02-25 EP disclosed
US-5928785-A ACRYLIC POLYMER WITH POLAR GROUPS SELECTED FROM SULFONIC ACID GROUP, CARBOXYL CROUP AND PHOSPHORIC ACID GROUP JAPAN EXLAN COMPANY LIMITED (JP) 1999-07-27 US disclosed
EP-0841415-A2 Fine inorganic particles containing fibres and method for forming the same JAPAN EXLAN COMPANY LIMITED (JP) 1998-05-13 EP disclosed
US-5472818-A Comprising vinyl monomer, ring-opening polymerizable monomer and polyester; microspheres; toners for electrography TOYO BOSEKI KABUSHIKI KAISHA (JP) 1995-12-05 US disclosed
US-5382624-A Addition polymerization within polyester particle in dispersion, toners, electrography TOYO BOSEKI KABUSHIKI KAISHA (JP) 1995-01-17 US disclosed