Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554538 | 0.94 | THRA (0.44) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL27525281 | 0.86 | THRA (0.48) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL27583520 | 0.85 | THRA (0.47) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL18140034 | 0.82 | THRA (0.51) | THRATHRBPPARAPPARGLTB4R | |
| SCHEMBL18139549 | 0.82 | THRA (0.51) | THRATHRBPPARAPPARGLTB4R | |
| SCHEMBL11564578 | 0.82 | THRA (0.48) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL18139744 | 0.82 | THRA (0.51) | THRATHRBPPARAPPARGLTB4R | |
| SCHEMBL18139167 | 0.82 | THRA (0.51) | THRATHRBPPARAPPARGLTB4R | |
| SCHEMBL18140948 | 0.82 | THRA (0.51) | THRATHRBPPARAPPARGLTB4R | |
| SCHEMBL18141046 | 0.82 | THRA (0.51) | THRATHRBPPARAPPARGLTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0884375-B1 | Reaction products of substituted carboxylic acylating agents and carboxylic reactants for use in fuels and lubricants | LUBRIZOL CORP (US) | 2004-12-29 | — | — | EP | disclosed |
| US-6818601-B1 | REACTION PRODUCT OF HYDROCARBON POLYMER GRAFTED WITH ALPHA,BETA-ETHYLENICALLY UNSATURATED CARBOXYLIC ACID AND AN AMINE | THE LUBRIZOL CORPORATION | 2004-11-16 | — | — | US | disclosed |
| EP-0899276-B1 | Low chlorine content compositions for use in lubricants and fuels | LUBRIZOL CORP (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6165235-A | Low chlorine content compositions for use in lubricants and fuels | THE LUBRIZOL CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| US-5912213-A | REACTION OF OLEFIN WITH CARBOXYLIC REACTANT FOR ACYLATION | THE LUBRIZOL CORPORATION (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0899276-A1 | Low chlorine content compositions for use in lubricants and fuels | The Lubrizol Corporation (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5851966-A | Reaction products of substituted carboxylic acylating agents and carboxylic reactants for use in fuels and lubricants | THE LUBRIZOL CORPORATION (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0884375-A1 | Reaction products of substituted carboxylic acylating agents and carboxylic reactants for use in fuels and lubricants | The Lubrizol Corporation (US) | 1998-12-16 | — | — | EP | disclosed |
| EP-0882783-A2 | Substituted carboxylic acylating agent compositions and derivatives thereof for use in lubricants and fuels | The Lubrizol Corporation (US) | 1998-12-09 | — | — | EP | disclosed |
| EP-0882782-A2 | Nitrogen-containing dispersant-viscosity improvers for lubricating oils | The Lubrizol Corporation (US) | 1998-12-09 | — | — | EP | disclosed |