Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.47 |
| ▸ | PGR | P06401 | 7/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612499 | 0.85 | PARP1 (0.47) | PARP1NR3C1PGRNR3C2AR | |
| SCHEMBL12505563 | 0.79 | NR3C1 (0.48) | PARP1NR3C1PGRNR3C2AR | |
| SCHEMBL30862506 | 0.78 | PARP1 (0.47) | PARP1NR3C1PGRNR3C2AR | |
| SCHEMBL5520778 | 0.77 | NR3C1 (0.49) | PARP1NR3C1PGRNR3C2AR | |
| SCHEMBL3688817 | 0.76 | NR3C1 (0.59) | PARP1NR3C1PGRNR3C2AR | |
| SCHEMBL1493940 | 0.76 | NR3C1 (0.65) | PARP1NR3C1PGRNR3C2AR | |
| SCHEMBL6555672 | 0.76 | NR3C1 (0.48) | PARP1NR3C1PGRNR3C2AR | |
| SCHEMBL7138992 | 0.75 | TDP1 (0.39) | PARP1NR3C1PGRNR3C2PTGS1 | |
| SCHEMBL304124 | 0.75 | NR3C1 (0.64) | PARP1NR3C1PGRNR3C2AR | |
| SCHEMBL303654 | 0.75 | NR3C1 (0.64) | PARP1NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133486-B1 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AG (DE) | 2004-12-22 | — | — | EP | disclosed |
| CN-1171883-C | Nonsteroidal antiinflammatories | ���ֹɷݹ�˾ | 2004-10-20 | — | — | CN | disclosed |
| CN-1334809-A | Non-steroidal anti-inflammatory drugs | SCHERING AG (DE) | 2002-02-06 | — | — | CN | disclosed |
| US-6323199-B1 | AROMATIC HETEROCYCLIC HYDROXY AMINES OR AMIDES FOR TREATMENT OF INFLAMMATION | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-11-27 | — | — | US | disclosed |
| EP-1133486-A2 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000032584-A2 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-06-08 | — | — | WO | disclosed |