Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554527 | 0.88 | MEN1 (0.57) | MEN1KMT2AATMCA1CA2 | |
| SCHEMBL579714 | 0.87 | OPRM1 (0.68) | MEN1KMT2AATMMAPTNPC1 | |
| SCHEMBL6554088 | 0.85 | CA1 (0.53) | MEN1KMT2AATMCA1CA2 | |
| SCHEMBL6540208 | 0.85 | MEN1 (0.73) | MEN1KMT2AATMCA1CA2 | |
| SCHEMBL6677345 | 0.84 | CA1 (0.53) | MEN1KMT2AATMCA1CA2 | |
| SCHEMBL6541001 | 0.83 | TBXA2R (0.62) | MEN1KMT2AATMCA1CA2 | |
| SCHEMBL6541617 | 0.81 | CA1 (0.58) | MEN1KMT2AATMCA1CA2 | |
| SCHEMBL6805116 | 0.81 | CA1 (0.63) | MEN1KMT2AATMCA1CA2 | |
| SCHEMBL597987 | 0.80 | CA1 (0.69) | MEN1KMT2AATMCA1CA2 | |
| SCHEMBL6540205 | 0.80 | CA1 (0.69) | MEN1KMT2AATMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |