Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23493920 | 0.89 | TSHR (0.68) | TSHRPTPN1THRBALDH1A1POLB | |
| SCHEMBL28387209 | 0.89 | TSHR (0.62) | TSHRPTPN1THRBALDH1A1MEN1 | |
| SCHEMBL4526188 | 0.87 | TSHR (0.69) | TSHRTHRBALDH1A1ALOX15POLB | |
| SCHEMBL1897951 | 0.86 | TSHR (0.58) | TSHRTHRBALDH1A1CYP3A4TDP1 | |
| SCHEMBL5941686 | 0.84 | TSHR (0.52) | TSHRPTPN1BLMLMNATHRB | |
| SCHEMBL29187279 | 0.84 | TSHR (0.56) | TSHRTHRBALDH1A1CYP3A4POLB | |
| SCHEMBL25220357 | 0.84 | TSHR (0.52) | TSHRPTPN1BLMLMNATHRB | |
| SCHEMBL6457085 | 0.84 | TSHR (0.56) | TSHRTHRBALDH1A1 | |
| SCHEMBL10400352 | 0.84 | TSHR (0.56) | TSHRTHRBALDH1A1CYP3A4POLB | |
| SCHEMBL2781460 | 0.84 | TSHR (0.61) | TSHRPTPN1BLMLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278724-B1 | COMPOSITION OF POLYSULFIDES HAVING A REDUCED ODOR LEVEL | LUBRIZOL CORP (US) | 2004-12-22 | — | — | EP | disclosed |
| EP-1278724-A1 | COMPOSITION OF POLYSULFIDES HAVING A REDUCED ODOR LEVEL | The Lubrizol Corporation (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6362374-B1 | HYDROCARBYL ACRYLATES AS ODOR INHIBITORS | THE LUBRIZOL CORPORATION | 2002-03-26 | — | — | US | disclosed |
| WO-2001083435-A1 | COMPOSITION OF POLYSULFIDES HAVING A REDUCED ODOR LEVEL | THE LUBRIZOL CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |