⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851726 | 0.85 | — | — | |
| SCHEMBL1717782 | 0.79 | — | — | |
| SCHEMBL2369748 | 0.75 | FDPS (0.34) | — | |
| SCHEMBL3502976 | 0.72 | FDPS (0.44) | — | |
| SCHEMBL3502980 | 0.72 | FDPS (0.44) | — | |
| SCHEMBL10655090 | 0.72 | FDPS (0.44) | — | |
| SCHEMBL321873 | 0.72 | FDPS (0.44) | — | |
| SCHEMBL8531341 | 0.70 | TDP1 (0.33) | — | |
| SCHEMBL9846434 | 0.67 | — | — | |
| SCHEMBL1941428 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000950-B1 | Novel indanylidene compounds | HOFFMANN LA ROCHE (CH) | 2004-02-25 | — | — | EP | disclosed |
| EP-0933376-B1 | Silanyl-triazines as light screening compositions | HOFFMANN LA ROCHE (CH) | 2003-08-20 | — | — | EP | disclosed |
| US-6416746-B1 | ULTRAVIOLET RAY AND LIGHT SCREENING MATERIAL GRAFTED TO SILANE, OLIGOSILOXANE, OR POLYSILOXANE WITH IMPROVED SOLUBILITY AND LITTLE PENETRATION; FOR USE IN COSMETICS | ROCHE VITAMINS INC. | 2002-07-09 | — | — | US | disclosed |
| EP-1000950-A2 | Novel indanylidene compounds | F. HOFFMANN-LA ROCHE AG (CH) | 2000-05-17 | — | — | EP | disclosed |
| US-6018044-A | TRIS((ALKYL, SILANE, OLIGOSILOXANE OR POLYSILOXANE)(OXY OR AMINO)CARBONYL-(1,4-PHENYLENE)-AMINO)-S-TRIAZINES HAVING AT LEAST ONE SILICON CONTAINING MOIETY OF GIVEN FORMULA; USE AS UV-B FILTERS IN LIGHT SCREENING COMPOSITIONS | ROCHE VITAMINS INC. (US) | 2000-01-25 | — | — | US | disclosed |
| EP-0933376-A2 | Silanyl-triazines as light screening compositions | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-04 | — | — | EP | disclosed |
| US-4687748-A | Magnetic carbohydrate particles as carriers for affinity separation purposes | GAMBRO LUNDIA AB (SE) | 1987-08-18 | — | — | US | disclosed |