SCHEMBL6555099

SCHEMBL6555099

CCN(CC)CCN(CC)c1cc[c]cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
TSHR P16473 3/20 0.38
PSMD14 O00487 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
RECQL P46063 1/20 0.38
GFER P55789 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH3A1 P30838 1/20 0.35
ALDH1A3 P47895 1/20 0.35
CNR2 P34972 1/20 0.35
KDM4E B2RXH2 2/20 0.33
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD1 P21728 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11331244 0.84 ALDH1A1 (0.38) ALDH1A1TSHRPSMD14CYP3A4MAPK1
SCHEMBL4722449 0.83 ALDH1A1 (0.40) ALDH1A1TSHRPSMD14CYP3A4MAPK1
SCHEMBL20957 0.83 ALDH1A1 (0.52) ALDH1A1TSHRPSMD14CYP3A4MAPK1
SCHEMBL11323269 0.81 CNR2 (0.58) ALDH1A1TSHRMAPK1TDP1CNR2
SCHEMBL28822515 0.81 ALDH1A1 (0.50) ALDH1A1TSHRPSMD14CYP3A4MAPK1
SCHEMBL2456296 0.80 ALDH1A1 (0.38) ALDH1A1TSHRPSMD14CYP3A4MAPK1
SCHEMBL3039791 0.80 KMT2A (0.41) ALDH1A1TSHRPSMD14CYP3A4MAPK1
SCHEMBL11141853 0.79 TSHR (0.55) ALDH1A1TSHRCNR2KDM4ECHRM2
SCHEMBL6555127 0.78 ALDH1A1 (0.38) ALDH1A1TSHRPSMD14CYP3A4MAPK1
SCHEMBL2459645 0.77 CNR2 (0.42) TDP1CNR2KDM4EKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1234007-B1 OLIGOMERIC METHINE DYES CLARIANT FINANCE BVI LTD (VG) 2004-02-18 EP disclosed
EP-1234007-A1 OLIGOMERIC METHINE DYES Clariant Finance (BVI) Limited (VG) 2002-08-28 EP disclosed
WO-2001036543-A1 OLIGOMERIC METHINE DYES CLARIANT FINANCE (BVI) LIMITED (VG) 2001-05-25 WO disclosed
US-4256458-A DIMERIC PYRIDINIUM DYES BASF AKTIENGESELLSCHAFT (DE) 1981-03-17 US disclosed