Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 14/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241217 | 0.86 | CCR2 (0.68) | CCR2ALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL319610 | 0.86 | CCR2 (0.68) | CCR2ALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL3487757 | 0.86 | CCR2 (0.68) | CCR2ALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL7238858 | 0.84 | CCR2 (0.71) | CCR2ALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL3126608 | 0.82 | CCR2 (0.61) | CCR2ALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL12443556 | 0.81 | CCR2 (0.65) | CCR2ALDH1A1RAB9ANPC1 | |
| SCHEMBL7973568 | 0.81 | CCR2 (0.66) | CCR2ALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL8317734 | 0.81 | CCR2 (0.69) | CCR2ALDH1A1RAB9ANPC1 | |
| SCHEMBL7973572 | 0.81 | CCR2 (0.66) | CCR2ALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL3954242 | 0.81 | CCR2 (0.69) | CCR2ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214345-B1 | AGENTS FOR TREATING HUMAN DISEASES, ESPECIALLY FOR TREATING TUMORS SUCH AS COLONIC CANCERS AND MELANOMAS OR FOR REGENERATING TISSUE AND PROMOTING HAIR GROWTH | MAX DELBRUECK CENTRUM (DE) | 2004-12-29 | — | — | EP | claimed |