Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.55 |
| ▸ | NOS2 | P35228 | 1/20 | 0.54 |
| ▸ | FOS | P01100 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | JUN | P05412 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037296 | 0.88 | TAAR1 (0.56) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL19565620 | 0.88 | TAAR1 (0.59) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL17619335 | 0.87 | TAAR1 (0.63) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL17124212 | 0.87 | ALOX15 (0.63) | TAAR1TSHRMAPK1MTNR1AMTNR1B | |
| SCHEMBL5072123 | 0.86 | TAAR1 (0.76) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL9281549 | 0.86 | TAAR1 (0.76) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL15677257 | 0.86 | TAAR1 (0.61) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL32679864 | 0.85 | ATM (0.58) | CYP3A4 | |
| SCHEMBL3470956 | 0.84 | TAAR1 (0.59) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL17780116 | 0.82 | PTPN1 (0.82) | TAAR1TSHRMAPK1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214327-B1 | BLOCKED PHENYLALKYL SILANES | CROMPTON CORP (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6559329-B2 | Deblocking of a trialkoxysilane compound acontaining carbonate or acetooxy group is done by hydrolysis or alcoholyis | CROMPTON CORPORATION | 2003-05-06 | — | — | US | disclosed |
| US-6413646-B1 | Blocked phenolic silanes | CROMPTON CORPORATION | 2002-07-02 | — | — | US | disclosed |
| EP-1214327-A1 | BLOCKED PHENOLIC SILANES | Crompton Corporation (US) | 2002-06-19 | — | — | EP | disclosed |
| US-20020051890-A1 | Blocked phenolic silanes | WITCO CORPORATION | 2002-05-02 | — | — | US | disclosed |
| WO-2001009145-A1 | BLOCKED PHENOLIC SILANES | CROMPTON CORPORATION (US) | 2001-02-08 | — | — | WO | disclosed |