Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 9/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553577 | 0.89 | ADORA2B (0.42) | ADORA2BADORA3ADORA2AMEN1KMT2A | |
| SCHEMBL6049606 | 0.86 | ADORA2B (0.51) | ADORA2BADORA3ADORA2AADORA1 | |
| SCHEMBL6049625 | 0.86 | ADORA2B (0.50) | ADORA2BADORA3ADORA2AADORA1 | |
| SCHEMBL6553631 | 0.84 | ADORA2B (0.38) | ADORA2BADORA3ADORA2AADORA1GAA | |
| SCHEMBL6049598 | 0.84 | ADORA2B (0.44) | ADORA2BADORA3ADORA2AMEN1KMT2A | |
| SCHEMBL17691164 | 0.84 | ADORA2B (0.44) | ADORA2BADORA3ADORA2AMEN1KMT2A | |
| SCHEMBL6049561 | 0.84 | ADORA2B (0.41) | ADORA2BADORA3ADORA2AADORA1P2RY12 | |
| SCHEMBL6049553 | 0.84 | ADORA2B (0.39) | ADORA2BADORA3ADORA2AMEN1KMT2A | |
| SCHEMBL6049595 | 0.82 | ADORA2B (0.52) | ADORA2BADORA3ADORA2AMEN1KMT2A | |
| SCHEMBL6049644 | 0.82 | ADORA2B (0.47) | ADORA2BADORA3ADORA2AADORA1P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104422-B1 | PHENYL XANTHINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-02-18 | — | — | EP | disclosed |