Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.88 |
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL6838001 | 1.00 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL27633677 | 0.97 | ALDH1A1 (0.83) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL28826325 | 0.97 | ALDH1A1 (0.83) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL28860657 | 0.95 | ALDH1A1 (0.79) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL1243198 | 0.94 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL1243199 | 0.94 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL7155667 | 0.94 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL15660063 | 0.94 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL591542 | 0.94 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL6429505 | 0.94 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221964-A | Self-healing hydrogel with rapid gel capability and preparation method thereof | 武汉纺织大学 | 2024-06-21 | — | — | CN | claimed |
| CN-117813499-A | Method for measuring cobalt content in cobaltosic oxide material | 广东邦普循环科技有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-109541615-A | A kind of rust-proof effect is good and computer based agricultural product volume rapid measurement device | 柳州博泽科技有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-107338427-A | A kind of preparation method of electric parts powdered-metal passivator | 苏州莱特复合材料有限公司 | 2017-11-10 | — | — | CN | claimed |
| CN-105968919-A | Water-based antirust paint for metals | 任新根 | 2016-09-28 | — | — | CN | claimed |
| CN-104877487-A | Medical waterproof corrosion-resistant anti-rusting coating and preparation method thereof | SUZHOU BEC BIOLOGICAL TECHNOLOGY CO LTD | 2015-09-02 | — | — | CN | claimed |
| CN-103627235-A | Acrylic acid anti-rust coating | WUJIANG LINSU PREC MACHINERY CO LTD | 2014-03-12 | — | — | CN | claimed |
| CN-103627264-A | Polystyrene antirust paint | WUJIANG LINSU PREC MACHINERY CO LTD | 2014-03-12 | — | — | CN | claimed |
| CN-1829683-A | Mildronate, preparation method thereof and pharmaceutical composition based on mildronate | GRINDEKS JSC (LV) | 2006-09-06 | — | — | CN | claimed |
| CN-1256629-C | Composition for removing etching resisting agent and byproducts and use thereof | SAMSUNG ELECTRONICS CO LTD (KR) | 2006-05-17 | — | — | CN | claimed |
| CN-1407409-A | Composition for removing etching resisting agent and byproducts and use thereof | SAMSUNG ELECTRONICS CO LTD (KR) | 2003-04-02 | — | — | CN | claimed |
| JP-56133473-A | — | — | None | — | — | JP | disclosed |
| CN-118221964-A | Self-healing hydrogel with rapid gel capability and preparation method thereof | 武汉纺织大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-118221964-A | Self-healing hydrogel with rapid gel capability and preparation method thereof | 武汉纺织大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-117813499-A | Method for measuring cobalt content in cobaltosic oxide material | 广东邦普循环科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| US-20060037754-A1 | Gelled liquid hydrocarbon treatment fluids having reduced phosphorus volatility and their associated methods of use and preparation | HALLIBURTON ENERGY SERVICES, INC. | 2006-02-23 | — | — | US | disclosed |
| US-20050250652-A1 | Gelled invert emulsion compositions and methods of use and manufacture | HALLIBURTON ENERGY SERVICES, INC. | 2005-11-10 | — | — | US | disclosed |
| WO-2005106197-A1 | GELLED INVERT EMULSION COMPOSITIONS AND METHODS OF USE AND MANUFACTURE | HALLIBURTON ENERGY SERVICES, INC. (US) | 2005-11-10 | — | — | WO | disclosed |
| CN-1407409-A | Composition for removing etching resisting agent and byproducts and use thereof | SAMSUNG ELECTRONICS CO LTD (KR) | 2003-04-02 | — | — | CN | disclosed |
| JP-S56133473-A | CORROSION PREVENTING METHOD METAL | KATAYAMA CHEM WORKS CO LTD | 1981-10-19 | — | — | JP | disclosed |