Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555582 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1ATMBCHE | |
| SCHEMBL6553333 | 0.91 | MEN1 (0.56) | ALDH1A1KMT2AMEN1BCHEACHE | |
| SCHEMBL6553342 | 0.91 | MEN1 (0.56) | ALDH1A1KMT2AMEN1BCHEACHE | |
| SCHEMBL6554873 | 0.90 | SMN1; SMN2 (0.48) | ALDH1A1KMT2AMEN1ATMBCHE | |
| SCHEMBL6554864 | 0.90 | SMN1; SMN2 (0.48) | ALDH1A1KMT2AMEN1ATMBCHE | |
| SCHEMBL7160742 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL6555037 | 0.86 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL6555033 | 0.86 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1ATMSMN1; SMN2 | |
| Cyclopropane SCHEMBL7160745 | 0.82 | ALDH1A1 (0.47) | ALDH1A1BCHEACHESMN1; SMN2 | |
| SCHEMBL6553296 | 0.81 | KMT2A (0.51) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135369-B1 | ALPHA-SULFIN- AND ALPHA-SULFONAMINO ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-25 | — | — | EP | disclosed |
| US-6538159-B2 | For use in protecting plants against infestation by phytopathogenic microorganisms | SYNGENTA PARTICIPATIONS AG (CH) | 2003-03-25 | — | — | US | disclosed |
| US-20020099241-A1 | For use in protecting plants against infestation by phytopathogenic microorganisms | SYNGENTA PARTICIPATIONS AG (CH) | 2002-07-25 | — | — | US | disclosed |
| EP-1135369-A2 | ALPHA-SULFIN- AND ALPHA-SULFONAMINO ACID AMIDES | Syngenta Participations AG (CH) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000032569-A2 | ALPHA-SULFIN- AND ALPHA-SULFONAMINO ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099241-A1 | For use in protecting plants against infestation by phytopathogenic microorganisms | CBR1, CBR3, MSR1 | ALDH1A1 619/4885KMT2A 2523/4885MEN1 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.