Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 13/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 13/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554509 | 0.75 | EPHX2 (0.46) | MRGPRX4 | |
| SCHEMBL6554549 | 0.74 | SLC6A9 (0.46) | MRGPRX4NPC1RAB9APTGER1MET | |
| Hydrochloric Acid SCHEMBL6554810 | 0.74 | SLC6A9 (0.45) | MRGPRX4NPC1RAB9APTGER1MET | |
| SCHEMBL6330920 | 0.71 | MRGPRX4 (0.47) | MRGPRX4PDCD1CD274PTGER1 | |
| SCHEMBL6554651 | 0.70 | HPGD (0.45) | MRGPRX4NPC1RAB9APTGER1MET | |
| SCHEMBL6554696 | 0.69 | PPARG (0.41) | MRGPRX4 | |
| SCHEMBL6555857 | 0.68 | SLC6A9 (0.43) | MRGPRX4NPC1RAB9APDCD1CD274 | |
| SCHEMBL1978691 | 0.68 | MAOB (0.55) | PTGDR2MRGPRX4NPC1RAB9APDCD1 | |
| SCHEMBL6554874 | 0.68 | MAOB (0.55) | PTGDR2MRGPRX4PTGER1 | |
| SCHEMBL6332053 | 0.68 | MRGPRX4 (0.52) | PTGDR2MRGPRX4PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390357-A2 | ANTI-THROMBOTIC COMPOUNDS, PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002062778-A2 | ANTI-THROMBOTIC COMPOUNDS, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-08-15 | — | — | WO | disclosed |