Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 6/20 | 0.53 |
| ▸ | PPARA | Q07869 | 6/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955348 | 0.94 | MAPK1 (0.63) | MAPK1HTTSMN1; SMN2GAAMEN1 | |
| SCHEMBL6555749 | 0.91 | PPARG (0.64) | MAPK1HTTSMN1; SMN2GAAMEN1 | |
| SCHEMBL6957070 | 0.85 | MAPK1 (0.60) | MAPK1HTTSMN1; SMN2GAAMEN1 | |
| SCHEMBL6948903 | 0.85 | MAPK1 (0.57) | MAPK1HTTSMN1; SMN2GAAMEN1 | |
| SCHEMBL6555846 | 0.84 | PPARA (0.60) | SMN1; SMN2GAAMEN1KMT2ACYP2C9 | |
| SCHEMBL6555809 | 0.83 | PPARA (0.58) | GAAPPARGPPARAPPARD | |
| SCHEMBL6955465 | 0.81 | MAPK1 (0.59) | MAPK1HTTSMN1; SMN2GAAMEN1 | |
| SCHEMBL6956607 | 0.81 | HTT (0.63) | MAPK1HTTSMN1; SMN2GAAMEN1 | |
| SCHEMBL6947088 | 0.80 | PPARA (0.54) | KMT2AALDH1A1HPGDPPARGPPARA | |
| SCHEMBL6951014 | 0.80 | SMN1; SMN2 (0.50) | MAPK1HTTSMN1; SMN2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073643-B1 | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-12-29 | — | — | EP | claimed |