Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556018 | 0.94 | MAPK1 (0.59) | MAPK1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6555749 | 0.91 | PPARG (0.64) | MAPK1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6952971 | 0.84 | SMN1; SMN2 (0.65) | MAPK1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6948727 | 0.84 | PPARG (0.56) | RAB9APPARGPPARAPPARD | |
| SCHEMBL6957070 | 0.83 | MAPK1 (0.60) | MAPK1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6950858 | 0.81 | MAPK1 (0.60) | MAPK1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6948903 | 0.81 | MAPK1 (0.57) | MAPK1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6955465 | 0.80 | MAPK1 (0.59) | MAPK1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6957110 | 0.80 | MAPK1 (0.62) | MAPK1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6956607 | 0.80 | HTT (0.63) | MAPK1HTTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |