Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448044 | 0.97 | HIF1A (0.35) | ADRB1SIGMAR1ADRB2NCF1PLD1 | |
| SCHEMBL25753249 | 0.89 | — | — | |
| SCHEMBL104919 | 0.81 | ADRB1 (0.33) | ADRB1SIGMAR1HPGD | |
| SCHEMBL9582917 | 0.81 | ADRB1 (0.33) | ADRB1SIGMAR1HPGD | |
| SCHEMBL3888868 | 0.81 | ADRB1 (0.33) | ADRB1SIGMAR1HPGD | |
| Hydrochloric Acid SCHEMBL2422010 | 0.79 | HPGD (0.33) | ADRB1SIGMAR1HPGD | |
| SCHEMBL22375421 | 0.79 | HIF1A (0.35) | ADRB1SIGMAR1 | |
| Bromide SCHEMBL4160212 | 0.79 | ADRB1 (0.32) | ADRB1SIGMAR1 | |
| SCHEMBL14805909 | 0.79 | HIF1A (0.35) | ADRB1SIGMAR1 | |
| SCHEMBL21496037 | 0.77 | ADRB1 (0.31) | ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490051-A1 | USE OF TOPOISOMERASE INHIBITORS AND HEAT SHOCK PROTEIN 90 INHIBITORS FOR USE IN CHEMOTHERAPY | THE UNIVERSITY OF LIVERPOOL (GB) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003082266-A1 | USE OF TOPOISOMERASE INHIBITORS AND HEAT SHOCK PROTEIN 90 INHIBITORS FOR USE IN CHEMOTHERAPY | UNIVERSITY OF LIVERPOOL (GB) | 2003-10-09 | — | — | WO | disclosed |