Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775956 | 0.85 | NR3C1 (0.67) | NR3C1NR3C2PGR | |
| SCHEMBL1775018 | 0.85 | NR3C1 (0.67) | NR3C1NR3C2PGR | |
| SCHEMBL1775343 | 0.85 | NR3C1 (0.67) | NR3C1NR3C2PGR | |
| SCHEMBL5780730 | 0.82 | NR3C2 (0.43) | NR3C1NR3C2PGR | |
| SCHEMBL3536771 | 0.80 | POLB (0.46) | NR3C1NR3C2GLAL3MBTL1PGR | |
| SCHEMBL6554688 | 0.79 | NR3C1 (0.51) | NR3C1NR3C2PGRPDK1PDK2 | |
| SCHEMBL3532068 | 0.78 | NR3C2 (0.49) | NR3C1NR3C2PGR | |
| SCHEMBL6582083 | 0.77 | NR3C2 (0.49) | NR3C1NR3C2PGRPDK1PDK2 | |
| SCHEMBL5207875 | 0.77 | NR3C1 (0.53) | NR3C1NR3C2PGR | |
| SCHEMBL3536773 | 0.76 | MEN1 (0.44) | NR3C1NR3C2GLAL3MBTL1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133486-B1 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AG (DE) | 2004-12-22 | — | — | EP | disclosed |
| CN-1171883-C | Nonsteroidal antiinflammatories | ���ֹɷݹ�˾ | 2004-10-20 | — | — | CN | disclosed |
| CN-1334809-A | Non-steroidal anti-inflammatory drugs | SCHERING AG (DE) | 2002-02-06 | — | — | CN | disclosed |
| US-6323199-B1 | AROMATIC HETEROCYCLIC HYDROXY AMINES OR AMIDES FOR TREATMENT OF INFLAMMATION | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-11-27 | — | — | US | disclosed |
| EP-1133486-A2 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000032584-A2 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-06-08 | — | — | WO | disclosed |