Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 20/20 | 0.85 |
| ▸ | CMA1 | P23946 | 18/20 | 0.85 |
| ▸ | CTSG | P08311 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558220 | 0.96 | CTRC (0.91) | CTRCCMA1CTSG | |
| SCHEMBL8404958 | 0.94 | CTRC (0.90) | CTRCCMA1 | |
| SCHEMBL6556138 | 0.94 | CTRC (0.83) | CTRCCMA1CTSG | |
| SCHEMBL4458937 | 0.94 | CTRC (0.83) | CTRCCMA1CTSG | |
| SCHEMBL6556461 | 0.94 | CMA1 (0.84) | CTRCCMA1 | |
| SCHEMBL6558180 | 0.93 | CTRC (0.82) | CTRCCMA1CTSG | |
| SCHEMBL6558150 | 0.92 | CTRC (0.84) | CTRCCMA1CTSG | |
| SCHEMBL6556475 | 0.92 | CTRC (1.00) | CTRCCMA1 | |
| SCHEMBL6555873 | 0.90 | CTRC (0.81) | CTRCCMA1 | |
| SCHEMBL6556292 | 0.90 | CTRC (0.81) | CTRCCMA1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826671-B1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| US-5948785-A | USEFUL AS CHYMASE INHIBITORS AND CAN BE EFFECTIVE FOR THE PROPHYLAXIS AND TREATMENT OF VARIOUS DISEASES CAUSED BY CHYMASE, SUCH AS THOSE CAUSED BY ANGIOTENSIN II. | THE GREEN CROSS CORPORATION (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0826671-A1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | THE GREEN CROSS CORPORATION (JP) | 1998-03-04 | — | — | EP | disclosed |