Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 17/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556251 | 0.93 | ELANE (0.65) | ELANEP2RX3 | |
| SCHEMBL6557678 | 0.88 | ELANE (0.60) | ELANEP2RX3NPC1RAB9A | |
| SCHEMBL6556275 | 0.87 | ELANE (0.57) | ELANEP2RX3CASP1 | |
| SCHEMBL6556272 | 0.86 | ELANE (0.61) | ELANEP2RX3CASP1NPC1RAB9A | |
| SCHEMBL6558195 | 0.86 | ELANE (0.55) | ELANEP2RX3 | |
| SCHEMBL6556313 | 0.85 | ELANE (0.55) | ELANE | |
| SCHEMBL6557643 | 0.84 | ELANE (0.64) | ELANE | |
| SCHEMBL6558300 | 0.84 | ELANE (0.63) | ELANEP2RX3 | |
| SCHEMBL6556097 | 0.84 | ELANE (0.56) | ELANEP2RX3CASP1NPC1RAB9A | |
| SCHEMBL7155919 | 0.84 | ELANE (0.54) | ELANEP2RX3CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826671-B1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| EP-0826671-A1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | THE GREEN CROSS CORPORATION (JP) | 1998-03-04 | — | — | EP | disclosed |