Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3185551 | 0.80 | EPHX1 (0.38) | EPHX1ATMMAPK1ADORA2ATHRB | |
| Hydrochloric Acid SCHEMBL17156890 | 0.78 | EPHX1 (0.37) | EPHX1ATMMAPK1ADORA2A | |
| SCHEMBL10314187 | 0.77 | EPHX1 (0.46) | EPHX1ATMMAPK1ADORA2ALMNA | |
| SCHEMBL8135314 | 0.77 | EPHX1 (0.40) | EPHX1ATMMAPK1ADORA2A | |
| SCHEMBL18751250 | 0.76 | MEN1 (0.35) | LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8130345 | 0.75 | EPHX1 (0.39) | EPHX1ATMMAPK1 | |
| SCHEMBL21017756 | 0.74 | EPHX1 (0.35) | EPHX1ATM | |
| SCHEMBL10008936 | 0.73 | CYP2D6 (0.50) | EPHX1ATMMAPK1ADORA2ATHRB | |
| Sulfuric Acid SCHEMBL8582459 | 0.72 | ALOX15 (0.38) | EPHX1ATMMAPK1ADORA2A | |
| SCHEMBL2235856 | 0.71 | EPHX1 (0.38) | EPHX1ATMMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826671-B1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| US-5948785-A | USEFUL AS CHYMASE INHIBITORS AND CAN BE EFFECTIVE FOR THE PROPHYLAXIS AND TREATMENT OF VARIOUS DISEASES CAUSED BY CHYMASE, SUCH AS THOSE CAUSED BY ANGIOTENSIN II. | THE GREEN CROSS CORPORATION (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0826671-A1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | THE GREEN CROSS CORPORATION (JP) | 1998-03-04 | — | — | EP | disclosed |