Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | SNCA | P37840 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA3 | P07451 | 1/20 | 0.58 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27928903 | 1.00 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10PKM | |
| SCHEMBL27798264 | 0.87 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10PKM | |
| SCHEMBL6556435 | 0.83 | MAOB (0.66) | PTGS2CA12CA1CA2CA7 | |
| SCHEMBL6556432 | 0.83 | MAOB (0.66) | PTGS2CA12CA1CA2CA7 | |
| Sinapic Acid Methyl Ether SCHEMBL207442 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10PKM | |
| Sinapinate SCHEMBL15515158 | 0.81 | PKM (1.00) | KDM4EALDH1A1HPGDHSD17B10PKM | |
| SCHEMBL16189981 | 0.81 | KDM4E (0.74) | KDM4EALDH1A1HPGDHSD17B10PKM | |
| Sinapinate SCHEMBL27753908 | 0.81 | PKM (1.00) | KDM4EALDH1A1HPGDHSD17B10PKM | |
| Sinapinate SCHEMBL37312 | 0.81 | PKM (1.00) | KDM4EALDH1A1HPGDHSD17B10PKM | |
| Sinapinate SCHEMBL37313 | 0.81 | PKM (1.00) | KDM4EALDH1A1HPGDHSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103467281-B | A kind of phenol derivatives and application thereof | WUHAN INNERSE PHARMACEUTICALS CO., LTD. (CN) | 2016-03-23 | — | — | CN | disclosed |
| CN-103467281-A | Phenol derivative and application thereof | WUHAN INNERSE PHARMACEUTICALS CO LTD | 2013-12-25 | — | — | CN | disclosed |
| EP-0958285-B1 | TRICYCLIC BENZO[e]ISOINDOLES AND BENZO[h]ISOQUINOLINES | HOFFMANN LA ROCHE (CH) | 2004-01-07 | — | — | EP | disclosed |
| US-6310208-B1 | Serotonin receptor binding benzo[e]isoindoles and benzo[h]isoquinolines | HOFFMANN-LA ROCHE INC. | 2001-10-30 | — | — | US | disclosed |
| EP-0958285-A1 | TRICYCLIC BENZO[e]ISOINDOLES AND BENZO[h]ISOQUINOLINES | F.HOFFMANN-LA ROCHE AG (CH) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998030546-A1 | TRICYCLIC BENZO[e]ISOINDOLES AND BENZO[h]ISOQUINOLINES | F. HOFFMANN-LA ROCHE AG (CH) | 1998-07-16 | — | — | WO | disclosed |