Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10980506 | 0.88 | PTGS1 (0.47) | HPGDALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL27613551 | 0.86 | TRPM8 (0.48) | ACP3ADRA1DHPGDALDH1A1MEN1 | |
| SCHEMBL29538369 | 0.85 | PTGS1 (0.59) | ACP3HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL1917129 | 0.85 | PTGS1 (0.59) | ACP3HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL15641429 | 0.85 | PTGS1 (0.59) | ACP3HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL15695557 | 0.85 | PTGS1 (0.46) | ACP3ADRA1DHPGDALDH1A1MEN1 | |
| SCHEMBL2055566 | 0.83 | TRPM8 (0.52) | ACP3ADRA1DTRPM8OGG1PARP1 | |
| SCHEMBL10922688 | 0.83 | ACP3 (0.45) | ACP3ADRA1DHPGDALDH1A1MEN1 | |
| SCHEMBL27705790 | 0.83 | ACP3 (0.49) | ACP3ADRA1DHPGDALDH1A1MEN1 | |
| SCHEMBL27586341 | 0.82 | MAPT (0.48) | HPGDALDH1A1MEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704117-B1 | AZABICYCLO DERIVATIVES FOR TREATING OCULAR DISORDERS | ALCON INC (CH) | 2026-01-28 | — | — | EP | disclosed |
| US-12247028-B2 | Azabicyclo and diazepine derivatives | ALCON INC. (CH) | 2025-03-11 | — | — | US | disclosed |
| US-20240132497-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | ALCON INC. (CH) | 2024-04-25 | — | — | US | disclosed |
| US-11884666-B2 | Azabicyclo and diazepine derivatives | ALCON INC. (CH) | 2024-01-30 | — | — | US | disclosed |
| US-20220267328-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | ALCON INC. (CH) | 2022-08-25 | — | — | US | disclosed |
| US-11306090-B2 | Azabicyclo and diazepine derivatives | ALCON INC. (CH) | 2022-04-19 | — | — | US | disclosed |
| US-20210179616-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | ALCON INC. (CH) | 2021-06-17 | — | — | US | disclosed |
| US-20210179616-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | ALCON INC. (CH) | 2021-06-17 | — | — | US | disclosed |
| EP-3704117-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES FOR TREATING OCULAR DISORDERS | ALCON INC. (CH) | 2020-09-09 | — | — | EP | disclosed |
| CN-111247147-A | Azabicyclo and diazepatriene derivatives useful for treating ocular disorders | 爱尔康公司 | 2020-06-05 | — | — | CN | disclosed |
| EP-1423691-A1 | FLUORESCENCE BASED OXYGEN SENSOR SYSTEMS | 3M Innovative Properties Company (US) | 2004-06-02 | — | — | EP | disclosed |
| US-6664111-B2 | The detector is a solid polymeric matrix, e.g., siloxane, modified by a luminescent platinum group metal phenanthroline chelate complex which is quenchable by oxygen; blood and tissue samples; medical diagnosis; compact; lightweight | 3M INNOVATIVE PROPERTIES COMPANY | 2003-12-16 | — | — | US | disclosed |
| US-20030099574-A1 | Fluorescence based oxygen sensor systems | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-29 | — | — | US | disclosed |
| WO-2003019179-A1 | FLUORESCENCE BASED OXYGEN SENSOR SYSTEMS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884666-B2 | Azabicyclo and diazepine derivatives | CHRM3, CHRM5, CHRNA5 | ACP3 3863/4885ADRA1D 103/4885HPGD 1520/4885 |
| US-20240132497-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | CHRM3, CHRM5, CHRNA5 | ACP3 3863/4885ADRA1D 103/4885HPGD 1520/4885 |
| US-20210179616-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | CHRM3, CHRM5, CHRNA5 | ACP3 3863/4885ADRA1D 103/4885HPGD 1520/4885 |
| US-20220267328-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | CHRM3, CHRM5, CHRNA5 | ACP3 3863/4885ADRA1D 103/4885HPGD 1520/4885 |
| US-12247028-B2 | Azabicyclo and diazepine derivatives | CHRM3, CHRM5, CHRNA5 | ACP3 3863/4885ADRA1D 103/4885HPGD 1520/4885 |
| US-11306090-B2 | Azabicyclo and diazepine derivatives | CHRM3, CHRM5, CHRNA5 | ACP3 3863/4885ADRA1D 103/4885HPGD 1520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.