Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | FADS1 | O60427 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16527555 | 0.82 | IDO1 (0.51) | LMNAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL6556789 | 0.80 | MEN1 (0.46) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL232529 | 0.79 | MEN1 (0.53) | MEN1KMT2AHPGDPOLBKDM4E | |
| SCHEMBL11876679 | 0.78 | SMN1; SMN2 (0.48) | LMNAMEN1KMT2ASMN1; SMN2AKR1C3 | |
| SCHEMBL5030912 | 0.78 | EDNRA (0.55) | MEN1KMT2AHPGDSMN1; SMN2POLB | |
| SCHEMBL1041692 | 0.78 | AKR1C3 (0.51) | LMNAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL30407941 | 0.78 | EDNRA (0.52) | MEN1KMT2ASMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL4440732 | 0.77 | KDM4E (0.57) | LMNAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL11760014 | 0.77 | IDO1 (0.51) | LMNAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL823582 | 0.75 | SMN1; SMN2 (0.57) | LMNAMEN1KMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1197491-B1 | Thioxanthenone antitumor agents | SANOFI AVENTIS (FR) | 2004-12-29 | — | — | EP | disclosed |
| EP-0917458-B1 | LYOPHILIZED THIOXANTHENONE ANTIMUMOR AGENTS | SANOFI SYNTHELABO INC (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-0882723-B1 | Thioxanthenone antitumor agents | SANOFI SYNTHELABO (FR) | 2002-07-31 | — | — | EP | disclosed |
| EP-1197491-A1 | Thioxanthenone antitumor agents | SANOFI-SYNTHELABO (FR) | 2002-04-17 | — | — | EP | disclosed |
| EP-0619315-B1 | Thioxanthenone antitumor agents | SANOFI SA (FR) | 1999-06-09 | — | — | EP | disclosed |
| EP-0917458-A1 | LYOPHILIZED THIOXANTHENONE ANTIMUMOR AGENTS | SANOFI (FR) | 1999-05-26 | — | — | EP | disclosed |
| EP-0882723-A1 | Thioxanthenone antitumor agents | SANOFI (FR) | 1998-12-09 | — | — | EP | disclosed |
| US-5665760-A | Lyophilized thioxanthenone antitumor agents | SANOFI WINTHROP, INC. (US) | 1997-09-09 | — | — | US | disclosed |
| WO-1997010809-A1 | LYOPHILIZED THIOXANTHENONE ANTIMUMOR AGENTS | SANOFI (FR) | 1997-03-27 | — | — | WO | disclosed |
| US-5380749-A | Thioxanthenone antitumor agents | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0619315-A1 | Thioxanthenone antitumor agents | STERLING WINTHROP INC. (US) | 1994-10-12 | — | — | EP | disclosed |
| US-5346917-A | For mammals | STERLING WINTHROP INC. (US) | 1994-09-13 | — | — | US | disclosed |
| US-4539412-A | ANTITUMOR AGENTS | RENSSELAER POLYTECHNIC INSTITUTE (US) | 1985-09-03 | — | — | US | disclosed |